Verification Bias 

 
   Lead Investigator:    Michael Sachs
   Institution      :    previous NACC investigator
   E-Mail           :    michael.sachs@nih.gov
   Proposal ID      :    31


   Publications:


1  Sachs M, Koepsell TD
   Factors Associated with Brain Autopsy in a Large Multi-Center Sample of Decedents: A Multivariate Analysis
   Abstract  Alzheimers Dement,4:T712,2008,

   PUBLISHED



2  Sachs M
   Factors Associated with Brain Autopsy in a Large Sample of Decedents
   Abstract  Alzheimers Dement,6:S460-S461,2010,

   PUBLISHED





   Proposal Description:
   1. To develop new statistical methods to assess the accuracy of a continuous diagnostic  test in the presence of non-random selection of subjects for definitive diagnosis of  disease.  2. To extend ROC regression methods to accomodate non-random selection of subjects  for definitive diagnosis.  3. To apply statistical methods from (1) and (2) to the MDS.